Win+1, 2, 3, 4, etc.will launch each program in your taskbar. It is helpful then to keep your most used programs at the beginning of your task bar so you can open them one right after another. This also works in Windows Vista for the quick launch icons.
Win+Alt+1, 2, 3, etc.will open the jump list for each program in the taskbar. You can then use your arrows to select which jump list option you want to open.
Win+Twill cycle through taskbar programs. This is similar to just hovering over the item with your mouse but you can launch the program with Space or Enter.
Shift+F10opens the contextual or “right click” menu for a file/folder. This can be very handy for speed especially if you know which option you want to select. Look for an underlined letter in each option to know which letter you can press for faster access.
Shift+Deldeletes a file without sending it to the recycle bin because who wants to empty their recycle bin anyway?
Ctrl+Shift+Ncreates a new folder in your current directory.
Alt+Enteropens the file properties so you can view file size, sharing settings, and creation date.
F2renames a file or folder.
F3will open explorer and select the search bar. If you already have an explorer window open it will highlight the search bar. In some programs it will also open the search dialog to search within that program.
F6cycles objects in the current window. In explorer this will cycle between the location bar, options bar, left pane, and right pane. It also works with varying success in other programs.